梁华庚 副研究员（双聘）
华中科技大学材料科学与工程学院
湖北省武汉市洪山区珞喻路1037号，东一楼西侧二层
Tel/Fax: 86-27-87559826
E-mail: leonard19800318 (at) hust.edu.cn
教育经历和工作经历：
2021.1-至今 华中科技大学材料科学与工程学院，副研究员（双聘）
2023.3-至今 华中科技大学同济医学院附属协和医院，主任医师
2009.7-2023.2 华中科技大学同济医学院附属协和医院，主治医师, 副主任医师
2004.9-2009.7 华中科技大学，泌尿外科，博士
1998.9-2003.7 华中科技大学，临床医学，学士
近5年承担项目：
1. 国家重点研发计划，2018YFE0206900, 基于纳米孔芯片与手持式穿刺机器人的早期前列腺癌诊断技术研究，2020-2023, 在研，主持。
2. 国家自然科学基金，面上项目，12174136，基于多类分子识别的复合增强拉曼早期前列腺癌检测方法研究，2022-2025，在研，主持；
3. 国家自然科学基金，重大科研仪器研制项目，81927807，用于早期前列腺癌组织形态与功能研究的光-声-磁多模态成像系统，2020-2024，在研，子课题负责人。
4. 国家重点研发计划，2017YFB1303100，基于CT-三维超声导引的泌尿系肿瘤经皮穿刺手术机器人研究，2017-2021，已完成，子课题负责人。
近5年发表论文：
(1) Sun Z#, Zhang W, Ye Z, Yuan L, Fu M, Liu X, Liang H*, Han H*.NIR-II-triggered doxorubicin release for orthotopic bladder cancer chemo-photothermal therapy. Nanoscale. 2022. doi: 10.1039/d2nr04200b.
(2) Yin M#, Tong J#, Meng F, Liu C, Liu X, Fang F, He Z, Qin X, Liu C, Ni D, Gao Y*, Liang H*, Zhang X*, Luo L*.Near-Infrared-II activatable symbiotic 2D carbon-clay nanohybrids for dual imaging-guided combinational cancer therapy. ACS Appl Mater Interfaces. 2022. doi: 10.1021/acsami.2c11340.
(3) Ma Z#, Yang M, Foda MF, Zhang K, Li S, Liang H*, Zhao Y*, Han H*. Polarization of tumor-sssociated macrophages promoted by vitamin C-loaded liposomes for cancer immunotherapy. ACS Nano.2022, 16(10):17389–17401.
(4) Zhang T#, Liang H#, Wang Z, Qiu C, Peng YB, Zhu X, Li J, Ge X, Xu J, Huang X, Tong J, Ou-Yang J, Yang X, Li F*, Zhu B*.Piezoelectric ultrasound energy-harvesting device for deep brain stimulation and analgesia applications. Sci Adv.2022 15;8(15):eabk0159.
(5) Song H#, Wang J#, Xiong B, Hu J, Zeng P, Liu X, Liang H*. Biologically safe, versatile, and smart bismuthene functionalized with a drug delivery system based on red phosphorus quantum dots for cancer theranostics. Angew Chem Int Ed Engl. 2022:e202117679.
(6) Jing Guo#, Ruichen Shen, Xuejie Shen, Bo Zeng, Nianjun Yang, Huageng Liang∗, Yanbing Yang∗, Quan Yuan∗.Construction of high stability indium gallium zinc oxide transistor biosensors for reliable detection of bladder cancer-associated microRNA. Chinese Chemical Letters. 2022,33:979–982.
(7) Long H#, Qin X#, Xu R, Mei C, Xiong Z, Deng X, Huang K*, Liang H*. Non-modified ultrasound-responsive gas vesicles from microcystis with targeted tumor accumulation.Int J Nanomedicine. 2021;16:8405–8416.
(8)Zhaoyu Ma#, Mohamed F. Foda, Huageng Liang*, Yanli Zhao*, and Heyou Han*. In situ nanozyme-amplified NIR-II phototheranostics for tumor-specific imaging and therapy. Adv. Funct. Mater. 2021; 31(37): e2103765.
(9) Huiai Lu#, Chunlei Mei, Luhao Yang, Junyan Zheng, Junwei Tong, Fengsen Duan*, Huageng Liang*, Ling Hong*.PPM-18, an Analog of Vitamin K, Induces autophagy and apoptosis in bladder cancer cells through ROS and AMPK signaling pathways. Front Pharmacol. 2021;9:12: 684915.
(10) Cai K#, Zhang W, Foda MF, Li X, Zhang J, Zhong Y, Liang H*, Li H, Han H*, Zhai T*. Miniature hollow gold nanorods with enhanced effect for in vivo photoacoustic imaging in the NIR-II window. Small. 2020;16(37):e2002748.
(11) Duan F#, Mei C, Yang L, Zheng J, Lu H, Xia Y, Hsu S, Liang H*, Hong L*. Vitamin K2 promotes PI3K/AKT/HIF-1α-mediated glycolysis that leads to AMPK-dependent autophagic cell death in bladder cancer cells. Sci Rep. 2020;10(1):7714.
(12) Wang X#, Tong J#, He Z, Yang X, Meng F*, Liang H*, Zhang X*, Luo L*. Paclitaxel-Potentiated Photodynamic Theranostics for synergistic tumor ablation and precise anticancer efficacy monitoring. ACS Appl Mater Interfaces. 2020;12(5):5476–5487.
(13) Yingxue Lia#, Bo Zenga , Yujie Yang, Huageng Liang*, Yanbing Yang*，Yuan Quan*. Design of high stability thin-film transistor biosensor for the diagnosis of bladder cancer. Chinese Chemical Letters,2020, 31:1387–1391.
(14) Dong Hua#, Oleg N. Granichin, Xiaoping Zhang, Mingyue Ding, Huageng Liang∗, and Xuming Zhang∗. 3D motion planning for flexible needle insertion based on rapidly-exploring random trees with environment-adaptive sampling and central angle control. Journal of Medical Imaging and Health Informatics.2019,9, 1524–1533.
(15) Jinxia Ren#, Pavel Shcherbakov, Xiaoping Zhang, Mingyue Ding, Huageng Liang∗, and Xuming Zhang∗. An accurate detection method for biopsy needle in ultrasound images based on fuzzy enhancement and hough transform. Journal of Medical Imaging and Health Informatics. 2019,9, 1–5.
